The alternative text for this image may have been generated using AI. Therefore, novel methods are needed for fast and easy diagnosis of PML–RARA positive APL, without subjective interpretation steps.

该产品为PML/RARA融合基因检测试剂盒，属于第三类 体外诊断试剂，适用于定性检测 白血病 患者骨髓样本中的PML/RARA融合基因，主要用于患者分子分型的辅助诊断。 目前该产品处于注册申请受理阶段，后续还需经过技术审评、行政审批及核发批件等流程。

It has been shown that individual acute myeloid leukemia (AML) patients are characterized by one of few initiating DNA mutations and 5–10 cooperating mutations not yet defined among hundreds ...

本刊推荐：针对变异型急性早幼粒细胞白血病（APL）对标准疗法（ATRA/ATO）耐药这一临床难题，研究人员开展了TNRC18::RARA融合 ...

Rose Ann Padua, Jerome Larghero, Marie Robin, Carol le Pogam, Marie-Helene Schlageter, Sacha Muszlak, Jan Fric, Robert West, Philippe Rousselot, Thi Hai Phan ...

This action model could be activated in other types of cancers. The PML/RARA* protein causes the proliferation of cancer cells in patients affected by acute promyelocytic leukaemia. Existing targeted ...

Rose Ann Padua, Jerome Larghero, Marie Robin, Carol le Pogam, Marie-Helene Schlageter, Sacha Muszlak, Jan Fric, Robert West, Philippe Rousselot, Thi Hai Phan, Liesbeth Mudde, Helene Teisserenc, ...